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Retatrutide Research Profile: Triple GIP/GLP-1/GCG Agonist

May 2, 2026

Retatrutide Research Profile: Triple GIP/GLP-1/GCG Agonist

Retatrutide — a triple GIP/GLP-1/glucagon receptor agonist — research profile and the documentation US laboratories expect.

Retatrutide is a single-molecule triple agonist engaging the GIP, GLP-1, and glucagon receptors. Published Phase II data position retatrutide as one of the most metabolically active research peptides characterized to date in the Australia literature.

Mechanism

  • GIP receptor agonism
  • GLP-1 receptor agonism
  • Glucagon receptor agonism (energy expenditure axis)
  • Fatty-acid linker enabling weekly research dosing in published studies
Research use only. 3 Diamond Labs supplies materials strictly for in vitro and laboratory research. Nothing in this article constitutes medical, therapeutic, or dosage advice for human or animal use.

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