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Peptides for Weight Loss: Research Compounds Compared

May 7, 2026

Peptides for Weight Loss: Research Compounds Compared

Side-by-side research comparison of the leading weight-loss peptides studied in US laboratories — mechanism, half-life, and documentation.

Weight-loss peptides studied in the Australia are dominated by GLP-1 and multi-incretin receptor agonists, supplemented by lipolytic fragments such as AOD-9604. The table below summarizes the major documented profiles.

CompoundMechanismHalf-life (research)Reference dose range
TirzepatideGIP + GLP-1 agonist~5 days2.5–15 mg weekly
SemaglutideGLP-1 agonist~7 days0.25–2.4 mg weekly
RetatrutideGIP + GLP-1 + GCG agonist~6 daysPer published trial titration
AOD-9604Lipolytic hGH fragmentShortPer published research literature

Documentation common to all weight-loss research peptides

  • HPLC purity ≥98%
  • LC-MS confirmed identity
  • Counterion content
  • Endotoxin per analytical method
Research use only. 3 Diamond Labs supplies materials strictly for in vitro and laboratory research. Nothing in this article constitutes medical, therapeutic, or dosage advice for human or animal use.

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